I have a 2006 330 with late 2006 F250s and 1,100 hours.  Great boat.  Get about 1.1 to 1 gal when heading offshore canyon fishing - fully loaded, people, full tanks, water etc. Average trip to canyon 60 miles (burning 29 gph at 4800 rpms and 29-30 cruise) and trolling all day (burning 3.8 gph) and then returning home burns about 150-160 gallons of fuel.  With fuel prices at dock at $3.89 per gal yesterday, that’s roughly $600-650 per trip.  We absolutely love our boat and it rides very well with no slamming like we would occasionally get with my 2000 272 Sailfish I sold in 2012.  Having generator and air conditioning is a huge bonus!!!