Not sure if you ended up picking a prop yet or not, but just had my 1988 226 out yesterday with my newly mounted 2001 Evinrude DI 250. Running a 15.75 x 15 BRP Rebel prop with three guys, bimini up, 80 gallons of fuel or so, and a boatload of fishing gear, I was pulling 43.5 mph at 6000 rpm. I am slightly underpropped however, as I could easily exceed the max recommended WOT rpm of 6000. I chose the 15 pitch rebel as most folks had suggested it was an aggressive prop as it has quite a bit of blade area, aggressive cupping, and a larger diameter. This was with the engine mounted on the second highest mounting position (third bolt hole down).
I did not do extensive testing with my fuel flow, but it seemed like 3 mpg was a happy fuel economy, as I was computing 11 gph at 33 mph and 9 gph at 27 or so (both were nice cruise speeds). Frankly, I could probably go to the 17 pitch rebel, as I do not always run my boat with 3 guys and a full fuel load.