Trooper1,
I bought an '04 330 Express last April and couldn't be happier! The story behind the purchase has to do with my wife changing her mind about cruising. Originally had a Tiara, changed to a catamaran when she said go ahead and get a fishing only boat and then bought the Grady when she decided she liked cruising after all. Have not found the 225s to be any problem. Don't know if the extra 50hp for 250s would do anything other than reduce mileage.
We do have a gas generator that's been a bit of a problem. Unless you run it regularly, the seals will probably dry, crack and invite salt water in. It's also not real accessible for home maintenance.
Other than that, it's been terriffic.
Before purchase, I had the marina upgrade the overhead hatches in the cabin to the newer ones with sliding privacy curtain and screen as well as redo the arms on the captains chair.
I've also moved the freshwater hose from outside of the transom door to under the gunwale with a faucet connection. I tend to use fresh water for wash down even while fishing.
Also have a bimini that extends from the rocket launcher to the rear transom. folks told me it would get in the way of fishing but that hasn't turned out to be so.
You're looking at a great boat...if the price is right!